Efficacy of Clinical Trials
Efficacy of Clinical Trials
Where applicable, the efficacy of post-polio research in the fields explored on this page are rated as effective, or more research required, or not effective. There are currently 259 papers rated.

Activity Levels
Activity Levels
A selection of studies which focus on functional abilities and health related quality of life issues for polio survivors. There are currently 12 papers in this category.

Poliovirus
Acute Flaccid Paralysis
These papers discuss polio and other forms of acute flaccid paralysis, which is characterized by rapid onset of weakness of lower motor neurones. There are currently 5 papers in this category.

Ageing
Ageing
These studies explore the impact of ageing with LEoP and the prevalence and associations of secondary health conditions related to age. There are currently 9 papers in this category.

Anaerobic Threshold
Anaerobic Threshold
These studies determine whether the anaerobic threshold can be identified for post-polio clients in relation to offering individualized aerobic training. There is currently 0 paper in this category.

Anaesthesia
Anaesthesia
Studies on the use of common anaesthetics, neuromuscular blockade, regional anaesthesia, and general management strategies. There are currently 3 papers in this category.

Assistive Technology
Assistive Technology
Studies discussing the impact of assistive technology on symptom management, mobility, and quality of life. There are currently 8 papers in this category.

Brain
Brain
Studies looking at whether polio-encephalitis has produced permanent neuronal injury. There is currently 5 paper in this category.

Cardiorespiratory
Cardiorespiratory
These studies look at cardiopulmonary conditioning and programs to provide improved cardiac status. There are currently 4 papers in this category.

Cardiovascular
Cardiovascular
Studies exploring the prevalence of dyslipidaemia and other risk factors for coronary heart disease. There are currently 1 papers in this category.

Clinical Evaluation
Clinical Evaluation
Evaluating the association between self-reported severity of LEoP and current functional status among polio survivors. There is currently 1 paper in this category.

Cold Intolerance
Cold Intolerance
Studies looking at the impairment of sympathetic vasoconstrictor outflow in the post-polio population. There is currently 0 paper in this category.

Complementary Therapies
Complementary Therapies
These papers propose that polio survivors should have access to the treatments that they perceive as important. There are currently 10 papers in this category.

Continence
Continence
Studies looking at prevalence, correlation to gender and age, and the inconvenience experienced by polio survivors. There are currently 3 papers in this category.

Coping Strategies
Coping Styles & Strategies
Studies exploring lifestyle and personal changes in relation to the design and evaluation of appropriate rehabilitation programs. There are currently 2 papers in this category.

Cultural Context
Cultural Context
Cultural contexts that influence the ways individuals interpret and experience functional losses associated with the LEoP. There is currently 1 paper in this category.

Diagnosis and Management
Diagnosis and Management
These studies discuss the diagnoses of new LEoP problems, implications for treatment, and areas for future research. There are currently 61 papers in this category.

Differential Diagnosis
Differential Diagnosis
Studies discussing identification and treatment of other medical and neurological conditions which produce LEoP-like symptoms. There are currently 4 papers in this category.

Drugs
Drugs
Trials and studies on pharmacological therapy and intervention for post-polio symptoms. There are currently 18 papers in this category.

Dysphagia
Dysphagia
Studies assessing the occurrence of dysphagia in the post-polio population and related therapeutic programs. There are currently 1 papers in this category.

Dysphonia
Dysphonia
Studies presenting aetiologic theories and treatment recommendations of dysphonia in the post-polio population. There are currently 1 papers in this category.

Epidemiology
Epidemiology
These studies review the epidemiology relating to the highly infectious poliovirus, where one in 200 infections leads to irreversible paralysis. There is currently 2 paper in this category.

Exercise
Exercise
Studies evaluating effects of, and contraindications for, exercise in individuals with the LEoP, clinical assessment, and exercise prescription. There are currently 30 papers in this category.

Falls
Falls
Studies reviewing risk factors, occurrence, and consequences of falls amongst the post-polio population. There are currently 18 papers in this category.

Fatigue
Fatigue
Studies measuring fatigue in the post-polio population and suggestions for management strategies. There are currently 22 papers in this category.

Fractures
Fractures
Studies determining prevalence of osteoporosis, falls and fractures, and evaluating potential contributing factors to osteoporosis. There are currently 2 papers in this category.

Gender
Gender Differences
These papers explore whether gender could be a contributing factor to the progressive decline in muscle strength in persons with late effects of polio. There are currently 1 papers in this category.

Immune Response
Immune Response
Studies evaluating autoimmune processes following the initial polio infection. There are currently 4 papers in this category.

inflammation
Inflammation
Studies exploring the hypothesis of intrathecal chronic inflammation to explain the denervation observed in PPS. There are currently 5 papers in this category.

LEoP_400x259
Late Effects of Polio (LEoP)
The LEoP studies incorporate Post-Polio Syndrome (PPS) and Post-Polio Sequalae and relate to aetiology and neuromuscular function. There are currently 50 papers in this category.

Muscle Strength
Muscle Strength
These studies explore testing for muscle strength and the role of strengthening exercises for polio survivors. There are currently 19 papers in this category.

Muscular Atrophy
Muscular Atrophy
Studies that identify potential risk factors for the development of progressive post-polio muscular atrophy. There are currently 5 papers in this category.

Orthoses
Orthoses
Studies examining and evaluating gait symmetry in post-polio patients and the efficacy of various orthoses. There are currently 18 papers in this category.

Pain
Pain
Studies that analyse pain, both nociceptive and neuropathic, and make recommendations for multidisciplinary approaches to pain management. There are currently 12 papers in this category.

Polio Vaccine
Polio Immunisation
These studies discuss the types, efficacy, and safety of polio vaccines. There are currently 16 papers in this category.

Post-Polio Motor Unit
Post-Polio Motor Unit
Studies looking at distal degeneration of post-polio motor units with resultant irreversible muscle fibre denervation. There are currently 37 papers in this category.

Psychology
Psychology
Studies that examine prevalence of psychological distress and depression, and the associations among measures of psychosocial factors, pain, and adjustment. There are currently 21 papers in this category.

Lifestyle
Quality of Life
These studies explore topics including the impact of pain, fatigue, assistive technology, and hope on the Quality of Life (QOL) of polio patients. There are currently 34 papers in this category.

Kidneys
Renal Complications
These papers caution that polio survivors may have severe hyperkalemia muscle weakness and could have renal failure even with a normal creatinine level. There is currently 1 paper in this category.

Respiratory Management
Respiratory Management
Studies reviewing the diagnosis of sleep-disordered breathing in neuromuscular diseases, and optimising non-invasive ventilation settings. There are currently 21 papers in this category.

Restless Legs Syndrome
Restless Legs Syndrome
These studies investigate the prevalence of restless legs syndrome (RLS), fatigue and daytime sleepiness in polio survivors. There are currently 5 papers in this category.

Sleep Analysis
Sleep Analysis
Analysis of post-polio sleep characteristics and correlation with pain, fatigue, headache and daily hypersomnolence. There are currently 4 papers in this category.

Vitality
Surgery
Studies concerning surgery .... There is currently 14 paper in this category.

Vitality
Vitality
Studies evaluating vitality, and the relative contributions of physiological and psychological parameters to the level of vitality. There are currently 0 papers in this category.

Vocational Implications
Vocational Implications
These papers review the role of rehabilitation physicians and counsellors in assisting post-polio clients with work-oriented interventions. There are currently 8 papers in this category.